Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

Thousands of long noncoding RNAs (lncRNAs) have been discovered, yet the function of the vast majority remains unclear. Here, we show that a p53-regulated lncRNA which we named PINCR (p53-induced noncoding RNA), is induced ~100-fold after DNA damage and exerts a prosurvival function in human colorec...

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Detalles Bibliográficos
Autores principales: Chaudhary, Ritu, Gryder, Berkley, Woods, Wendy S, Subramanian, Murugan, Jones, Matthew F, Li, Xiao Ling, Jenkins, Lisa M, Shabalina, Svetlana A, Mo, Min, Dasso, Mary, Yang, Yuan, Wakefield, Lalage M, Zhu, Yuelin, Frier, Susan M, Moriarity, Branden S, Prasanth, Kannanganattu V, Perez-Pinera, Pablo, Lal, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470874/
https://www.ncbi.nlm.nih.gov/pubmed/28580901
http://dx.doi.org/10.7554/eLife.23244

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