Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545

Despite the high prevalence of acute kidney injury (AKI) and its association with increased morbidity and mortality, therapeutic approaches for AKI are disappointing. This is largely attributed to poor understanding of the pathogenesis of AKI. Heparanase, an endoglycosidase that cleaves heparan sulf...

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Detalles Bibliográficos
Autores principales: Abassi, Zaid, Hamoud, Shadi, Hassan, Ahmad, Khamaysi, Iyad, Nativ, Omri, Heyman, Samuel N., Muhammad, Rabia Shekh, Ilan, Neta, Singh, Preeti, Hammond, Edward, Zaza, Gianluigi, Lupo, Antonio, Onisto, Maurizio, Bellin, Gloria, Masola, Valentina, Vlodavsky, Israel, Gambaro, Giovani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470960/
https://www.ncbi.nlm.nih.gov/pubmed/28388547
http://dx.doi.org/10.18632/oncotarget.16573

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