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Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line

Malignant mesothelioma (MM) is a primary tumor arising from the serous membranes. The resistance of MM patients to conventional therapies, and the poor patients’ survival, encouraged the identification of molecular targets for MM treatment. Curcumin (CUR) is a “multifunctional drug”. We explored the...

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Detalles Bibliográficos
Autores principales: Masuelli, Laura, Benvenuto, Monica, Stefano, Enrica Di, Mattera, Rosanna, Fantini, Massimo, Feudis, Giuseppina De, Smaele, Enrico De, Tresoldi, Ilaria, Giganti, Maria Gabriella, Modesti, Andrea, Bei, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470978/
https://www.ncbi.nlm.nih.gov/pubmed/28159921
http://dx.doi.org/10.18632/oncotarget.14907