Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1

Mantle cell lymphoma (MCL) is an aggressive B-cell lymphoma with poor prognosis, characterized by aberrant expression of growth-regulating and oncogenic effectors and requiring novel anticancer strategies. The nuclear transporter exportin-1 (XPO1) is highly expressed in MCL and is associated with it...

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Detalles Bibliográficos
Autores principales: Sekihara, Kazumasa, Saitoh, Kaori, Han, Lina, Ciurea, Stefan, Yamamoto, Shinichi, Kikkawa, Mika, Kazuno, Saiko, Taka, Hikari, Kaga, Naoko, Arai, Hajime, Miida, Takashi, Andreeff, Michael, Konopleva, Marina, Tabe, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470990/
https://www.ncbi.nlm.nih.gov/pubmed/28388555
http://dx.doi.org/10.18632/oncotarget.16602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470990/
https://www.ncbi.nlm.nih.gov/pubmed/28388555
http://dx.doi.org/10.18632/oncotarget.16602

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