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Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling

Isoliquiritigenin (ISL), a member of the flavonoids, is known to have anti-tumor activity in vitro and in vivo. The effect of ISL on reprogramming in cancer cells, however, remains elusive. In this study, we investigated the effect of ISL on reprogramming in human melanoma A375 cells. ISL (15 μg/ml)...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao-Yu, Li, De-Fang, Han, Ji-Chun, Wang, Bo, Dong, Zheng-Ping, Yu, Li-Na, Pan, Zhao-Hai, Qu, Chuan-Jun, Chen, Ying, Sun, Shi-Guo, Zheng, Qiu-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470991/ https://www.ncbi.nlm.nih.gov/pubmed/28410220 http://dx.doi.org/10.18632/oncotarget.16655

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