Changes in T-cell subpopulations and cytokine network during early period of ibrutinib therapy in chronic lymphocytic leukemia patients: the significant decrease in T regulatory cells number

B cell receptor (BCR) stimulation signal plays an important role in the pathogenesis of chronic lymphocytic leukemia (CLL), and kinase inhibitors directed toward the BCR pathway are now the promising anti-leukemic drugs. Ibrutinib, a Bruton tyrosine kinase inhibitor, demonstrates promising clinical...

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Detalles Bibliográficos
Autores principales: Podhorecka, Monika, Goracy, Aneta, Szymczyk, Agnieszka, Kowal, Malgorzata, Ibanez, Blanca, Jankowska-Lecka, Olga, Macheta, Arkadiusz, Nowaczynska, Aleksandra, Drab-Urbanek, Elzbieta, Chocholska, Sylwia, Jawniak, Dariusz, Hus, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471000/
https://www.ncbi.nlm.nih.gov/pubmed/28416773
http://dx.doi.org/10.18632/oncotarget.16148

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