Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer

Cysteinyl leukotriene receptor 1 (CysLT(1)R) has been shown to be up-regulated in the adenocarcinomas of colorectal cancer patients, which is associated with a poor prognosis. In a spontaneous model of colon cancer, CysLT(1)R disruption was associated with a reduced tumor burden in double-mutant fem...

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Detalles Bibliográficos
Autores principales: Osman, Janina, Savari, Sayeh, Chandrashekar, Naveen Kumar, Bellamkonda, Kishan, Douglas, Desiree, Sjölander, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471010/
https://www.ncbi.nlm.nih.gov/pubmed/28410235
http://dx.doi.org/10.18632/oncotarget.16718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471010/
https://www.ncbi.nlm.nih.gov/pubmed/28410235
http://dx.doi.org/10.18632/oncotarget.16718

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