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Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer
Cysteinyl leukotriene receptor 1 (CysLT(1)R) has been shown to be up-regulated in the adenocarcinomas of colorectal cancer patients, which is associated with a poor prognosis. In a spontaneous model of colon cancer, CysLT(1)R disruption was associated with a reduced tumor burden in double-mutant fem...
Autores principales: | Osman, Janina, Savari, Sayeh, Chandrashekar, Naveen Kumar, Bellamkonda, Kishan, Douglas, Desiree, Sjölander, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471010/ https://www.ncbi.nlm.nih.gov/pubmed/28410235 http://dx.doi.org/10.18632/oncotarget.16718 |
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