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Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer
Precision medicine requires accurate multi-gene clinical diagnostics. We describe the implementation of an Illumina TruSight Tumor (TST) clinical NGS diagnostic framework and parallel validation of a NanoString RNA-based ALK, RET, and ROS1 gene fusion assay for combined analysis of treatment predict...
Autores principales: | Lindquist, Kajsa Ericson, Karlsson, Anna, Levéen, Per, Brunnström, Hans, Reuterswärd, Christel, Holm, Karolina, Jönsson, Mats, Annersten, Karin, Rosengren, Frida, Jirström, Karin, Kosieradzki, Jaroslaw, Ek, Lars, Borg, Åke, Planck, Maria, Jönsson, Göran, Staaf, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471012/ https://www.ncbi.nlm.nih.gov/pubmed/28415793 http://dx.doi.org/10.18632/oncotarget.16276 |
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