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Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer

Precision medicine requires accurate multi-gene clinical diagnostics. We describe the implementation of an Illumina TruSight Tumor (TST) clinical NGS diagnostic framework and parallel validation of a NanoString RNA-based ALK, RET, and ROS1 gene fusion assay for combined analysis of treatment predict...

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Detalles Bibliográficos
Autores principales:	Lindquist, Kajsa Ericson, Karlsson, Anna, Levéen, Per, Brunnström, Hans, Reuterswärd, Christel, Holm, Karolina, Jönsson, Mats, Annersten, Karin, Rosengren, Frida, Jirström, Karin, Kosieradzki, Jaroslaw, Ek, Lars, Borg, Åke, Planck, Maria, Jönsson, Göran, Staaf, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471012/ https://www.ncbi.nlm.nih.gov/pubmed/28415793 http://dx.doi.org/10.18632/oncotarget.16276

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