A potential anti-tumor effect of leukotriene C(4) through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Cyclooxygenase-2, which plays a key role in the biosynthesis of prostaglandin E(2) (PGE(2)), is often up-regulated in CRC and in other types of cancer. PGE(2) induces angiogenesis and tumor cell survival, prolif...

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Detalles Bibliográficos
Autores principales: Mehdawi, Lubna M., Satapathy, Shakti Ranjan, Gustafsson, Annika, Lundholm, Kent, Alvarado-Kristensson, Maria, Sjölander, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471032/
https://www.ncbi.nlm.nih.gov/pubmed/28402256
http://dx.doi.org/10.18632/oncotarget.16591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471032/
https://www.ncbi.nlm.nih.gov/pubmed/28402256
http://dx.doi.org/10.18632/oncotarget.16591

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