Cargando…

Gαi3 nuclear translocation causes irradiation resistance in human glioma cells

We have previously shown that Gαi3 is elevated in human glioma, mediating Akt activation and cancer cell proliferation. Here, we imply that Gαi3 could also be important for irradiation resistance. In A172 human glioma cells, Gαi3 knockdown (by targeted shRNAs) or dominant-negative mutation significa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Shang, Li, Ya, Bai, Jin-Yu, Zhang, Zhi-Qing, Wang, Yin, Qiao, Yin-Biao, Zhou, Xiao-Zhong, Yang, Bo, Tian, Ye, Cao, Cong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471034/ https://www.ncbi.nlm.nih.gov/pubmed/28456783 http://dx.doi.org/10.18632/oncotarget.17043

Ejemplares similares

Neuronal-driven glioma growth requires Gαi1 and Gαi3
por: Wang, Yin, et al.
Publicado: (2021)

YME1L overexpression exerts pro-tumorigenic activity in glioma by promoting Gαi1 expression and Akt activation
por: Liu, Fang, et al.
Publicado: (2022)

Requirement of Gαi1 and Gαi3 in interleukin-4-induced signaling, macrophage M2 polarization and allergic asthma response
por: Bai, Jin-yu, et al.
Publicado: (2021)

G protein inhibitory α subunit 2 is a molecular oncotarget of human glioma
por: Wang, Yin, et al.
Publicado: (2023)

G against Glioma: G protein inhibitory α subunit 2 (Gαi2) as a novel glioma target
por: Markopoulos, Georgios S.
Publicado: (2023)

Gαi1 and Gαi3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis
por: Sun, Jian, et al.
Publicado: (2018)

Identification of Gαi3 as a novel molecular therapeutic target of cervical cancer
por: Zhang, Jie, et al.
Publicado: (2022)

SCF/c-Kit-activated signaling and angiogenesis require Gαi1 and Gαi3
por: Shan, Hua-jian, et al.
Publicado: (2023)

Nuclear factor translocation and acute anterior uveitis
por: Wang, Jing, et al.
Publicado: (2011)

TAX1BP1 contributes to deoxypodophyllotoxin-induced glioma cell parthanatos via inducing nuclear translocation of AIF by activation of mitochondrial respiratory chain complex I
por: Wang, Xuan-zhong, et al.
Publicado: (2023)

Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease
por: Ju, Tz-Chuen, et al.
Publicado: (2011)

Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma
por: Grassi, Elisa Stellaria, et al.
Publicado: (2020)

YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions
por: Chang, Heng-Ai, et al.
Publicado: (2023)

The Nuclear Translocation of Heme Oxygenase-1 in Human Diseases
por: Yang, Qing, et al.
Publicado: (2022)

G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2
por: Fresia, Chiara, et al.
Publicado: (2016)

Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA
por: Kour, Smit, et al.
Publicado: (2021)

WITHAFERIN A INDUCES APOPTOSIS IN RAT C6 GLIOMA CELLS THROUGH REGULATING NF-KB NUCLEAR TRANSLOCATION AND ACTIVATION OF CASPASE CASCADE
por: Hou, Wei-chen, et al.
Publicado: (2017)

Prognostic implications of epidermal growth factor receptor variant III expression and nuclear translocation in Chinese human gliomas
por: Yang, Kaiyuan, et al.
Publicado: (2019)

G4LDB 2.2: a database for discovering and studying G-quadruplex and i-Motif ligands
por: Wang, Yu-Huan, et al.
Publicado: (2021)

Modulation and Visualization of EF‐G Power Stroke During Ribosomal Translocation
por: Yin, Heng, et al.
Publicado: (2019)

TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form
por: Thiyagarajan, Dhivya, et al.
Publicado: (2015)

BAG3 is required for IKKα nuclear translocation and emergence of castration resistant prostate cancer
por: Ammirante, M, et al.
Publicado: (2011)

Enhancement of Lymphangiogenesis In Vitro via the Regulations of HIF-1α Expression and Nuclear Translocation by Deoxyshikonin
por: Prangsaengtong, Orawin, et al.
Publicado: (2013)

PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX1
por: Li, Xuetao, et al.
Publicado: (2023)

USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2
por: Cai, Zeng, et al.
Publicado: (2020)

LMAP-10 RE-IRRADIATION FOR RECURRENT ADULT DIFFUSE GLIOMA
por: Zhou, Jiangfen, et al.
Publicado: (2023)

NCX2 Regulates Intracellular Calcium Homeostasis and Translocation of HIF-1α into the Nucleus to Inhibit Glioma Invasion
por: Liu, Hongyuan, et al.
Publicado: (2022)

RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11
por: Zhang, Yarui, et al.
Publicado: (2022)

Identification of Gαi3 as a promising target for osteosarcoma treatment
por: Bian, Zheng-jun, et al.
Publicado: (2022)

Gαi1/3 mediation of Akt-mTOR activation is important for RSPO3-induced angiogenesis
por: Xu, Gang, et al.
Publicado: (2022)

Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death
por: Jeong, Ji C, et al.
Publicado: (2011)

β-catenin nuclear translocation induced by HIF-1α overexpression leads to the radioresistance of prostate cancer
por: Luo, Yong, et al.
Publicado: (2018)

The key role of microtubules in hypoxia preconditioning-induced nuclear translocation of HIF-1α in rat cardiomyocytes
por: Guo, Hai, et al.
Publicado: (2017)

PTEN nuclear translocation enhances neuronal injury after hypoxia-ischemia via modulation of the nuclear factor-κB signaling pathway
por: Zhao, Jing, et al.
Publicado: (2021)

Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis
por: Li, Ya, et al.
Publicado: (2023)

A New Generation of FRET Sensors for Robust Measurement of Gα(i1), Gα(i2) and Gα(i3) Activation Kinetics in Single Cells
por: van Unen, Jakobus, et al.
Publicado: (2016)

Nuclear translocation of beta-catenin in colorectal cancer
por: Kobayashi, M, et al.
Publicado: (2000)

DNA damage induces nuclear translocation of parkin
por: Kao, Shyan-Yuan
Publicado: (2009)

Inhibition of p65 Nuclear Translocation by Baicalein
por: Seo, Min Bum, et al.
Publicado: (2011)

Mechanical Regulation of Nuclear Translocation in Migratory Neurons
por: Nakazawa, Naotaka, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_74e7bpavab9rajgik07evg2rb6