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IL-36 Receptor Deletion Attenuates Lung Injury and Decreases Mortality in Murine Influenza Pneumonia
Influenza virus causes a respiratory disease in human that can progress to lung injury with fatal outcome. The interleukin (IL)-36 cytokines are newly described IL-1 family cytokines that promote inflammatory responses via binding to the IL-36 receptor (IL-36R). The mechanism of expression and the r...
Autores principales: | Aoyagi, Tetsuji, Newstead, Michael W., Zeng, Xianying, Kunkel, Steven L., Kaku, Mitsuo, Standiford, Theodore J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471142/ https://www.ncbi.nlm.nih.gov/pubmed/27966554 http://dx.doi.org/10.1038/mi.2016.107 |
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