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Microfluidic co-cultures of retinal pigment epithelial cells and vascular endothelial cells to investigate choroidal angiogenesis

Angiogenesis plays a critical role in many diseases, including macular degeneration. At present, the pathological mechanisms remain unclear while appropriate models dissecting regulation of angiogenic processes are lacking. We propose an in vitro angiogenesis process and test it by examining the co-...

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Detalles Bibliográficos
Autores principales: Chen, Li-Jiun, Ito, Shuntaro, Kai, Hiroyuki, Nagamine, Kuniaki, Nagai, Nobuhiro, Nishizawa, Matsuhiko, Abe, Toshiaki, Kaji, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471206/
https://www.ncbi.nlm.nih.gov/pubmed/28615726
http://dx.doi.org/10.1038/s41598-017-03788-5