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Microfluidic co-cultures of retinal pigment epithelial cells and vascular endothelial cells to investigate choroidal angiogenesis
Angiogenesis plays a critical role in many diseases, including macular degeneration. At present, the pathological mechanisms remain unclear while appropriate models dissecting regulation of angiogenic processes are lacking. We propose an in vitro angiogenesis process and test it by examining the co-...
Autores principales: | Chen, Li-Jiun, Ito, Shuntaro, Kai, Hiroyuki, Nagamine, Kuniaki, Nagai, Nobuhiro, Nishizawa, Matsuhiko, Abe, Toshiaki, Kaji, Hirokazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471206/ https://www.ncbi.nlm.nih.gov/pubmed/28615726 http://dx.doi.org/10.1038/s41598-017-03788-5 |
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