(99m)Tc-labeled bevacizumab for detecting atherosclerotic plaque linked to plaque neovascularization and monitoring antiangiogenic effects of atorvastatin treatment in ApoE(−/−) mice

Atherosclerotic neovascularization plays a significant role in plaque instability as it provides additional lipids and inflammatory mediators to lesions, and resulting in intraplaque hemorrhage. Vascular endothelial growth factor-A (VEGF-A) is considered the predominant proangiogenic factor in angio...

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Detalles Bibliográficos
Autores principales: Tan, Hui, Zhou, Jun, Yang, Xiangdong, Abudupataer, Mieradilijiang, Li, Xiao, Hu, Yan, Xiao, Jie, Shi, Hongcheng, Cheng, Dengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471207/
https://www.ncbi.nlm.nih.gov/pubmed/28615707
http://dx.doi.org/10.1038/s41598-017-03276-w

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