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Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in plasma and myocardium of DCM patients and evaluated their effects on NFAT lucifer...

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Detalles Bibliográficos
Autores principales: Abraityte, Aurelija, Lunde, Ida G., Askevold, Erik T., Michelsen, Annika E., Christensen, Geir, Aukrust, Pål, Yndestad, Arne, Fiane, Arnt, Andreassen, Arne, Aakhus, Svend, Dahl, Christen P., Gullestad, Lars, Broch, Kaspar, Ueland, Thor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471231/
https://www.ncbi.nlm.nih.gov/pubmed/28615692
http://dx.doi.org/10.1038/s41598-017-03625-9