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Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways
Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP. Glucocorticoids are a type of steroid hormone that is used primarily in medical therapy f...
Autores principales: | Yang, Hyun-Woo, Lee, Seoung-Ae, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471256/ https://www.ncbi.nlm.nih.gov/pubmed/28615628 http://dx.doi.org/10.1038/s41598-017-02358-z |
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