Cargando…

rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?

Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magn...

Descripción completa

Detalles Bibliográficos
Autores principales: Rossi, Simone, Cappa, Stefano F., Ulivelli, Monica, De Capua, Alberto, Bartalini, Sabina, Rossini, Paolo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471538/
https://www.ncbi.nlm.nih.gov/pubmed/17148840
http://dx.doi.org/10.1155/2006/793256
_version_ 1783243966279319552
author Rossi, Simone
Cappa, Stefano F.
Ulivelli, Monica
De Capua, Alberto
Bartalini, Sabina
Rossini, Paolo M.
author_facet Rossi, Simone
Cappa, Stefano F.
Ulivelli, Monica
De Capua, Alberto
Bartalini, Sabina
Rossini, Paolo M.
author_sort Rossi, Simone
collection PubMed
description Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms.
format Online
Article
Text
id pubmed-5471538
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher IOS Press
record_format MEDLINE/PubMed
spelling pubmed-54715382017-07-02 rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? Rossi, Simone Cappa, Stefano F. Ulivelli, Monica De Capua, Alberto Bartalini, Sabina Rossini, Paolo M. Behav Neurol Research Article Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms. IOS Press 2006 2006-11-27 /pmc/articles/PMC5471538/ /pubmed/17148840 http://dx.doi.org/10.1155/2006/793256 Text en Copyright © 2006 Hindawi Publishing Corporation and the authors. http://creativecommons.org/licenses/by/3.0 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rossi, Simone
Cappa, Stefano F.
Ulivelli, Monica
De Capua, Alberto
Bartalini, Sabina
Rossini, Paolo M.
rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
title rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
title_full rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
title_fullStr rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
title_full_unstemmed rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
title_short rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
title_sort rtms for ptsd: induced merciful oblivion or elimination of abnormal hypermnesia?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471538/
https://www.ncbi.nlm.nih.gov/pubmed/17148840
http://dx.doi.org/10.1155/2006/793256
work_keys_str_mv AT rossisimone rtmsforptsdinducedmercifuloblivionoreliminationofabnormalhypermnesia
AT cappastefanof rtmsforptsdinducedmercifuloblivionoreliminationofabnormalhypermnesia
AT ulivellimonica rtmsforptsdinducedmercifuloblivionoreliminationofabnormalhypermnesia
AT decapuaalberto rtmsforptsdinducedmercifuloblivionoreliminationofabnormalhypermnesia
AT bartalinisabina rtmsforptsdinducedmercifuloblivionoreliminationofabnormalhypermnesia
AT rossinipaolom rtmsforptsdinducedmercifuloblivionoreliminationofabnormalhypermnesia