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rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?
Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magn...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471538/ https://www.ncbi.nlm.nih.gov/pubmed/17148840 http://dx.doi.org/10.1155/2006/793256 |
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author | Rossi, Simone Cappa, Stefano F. Ulivelli, Monica De Capua, Alberto Bartalini, Sabina Rossini, Paolo M. |
author_facet | Rossi, Simone Cappa, Stefano F. Ulivelli, Monica De Capua, Alberto Bartalini, Sabina Rossini, Paolo M. |
author_sort | Rossi, Simone |
collection | PubMed |
description | Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms. |
format | Online Article Text |
id | pubmed-5471538 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-54715382017-07-02 rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? Rossi, Simone Cappa, Stefano F. Ulivelli, Monica De Capua, Alberto Bartalini, Sabina Rossini, Paolo M. Behav Neurol Research Article Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms. IOS Press 2006 2006-11-27 /pmc/articles/PMC5471538/ /pubmed/17148840 http://dx.doi.org/10.1155/2006/793256 Text en Copyright © 2006 Hindawi Publishing Corporation and the authors. http://creativecommons.org/licenses/by/3.0 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Rossi, Simone Cappa, Stefano F. Ulivelli, Monica De Capua, Alberto Bartalini, Sabina Rossini, Paolo M. rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? |
title | rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? |
title_full | rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? |
title_fullStr | rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? |
title_full_unstemmed | rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? |
title_short | rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia? |
title_sort | rtms for ptsd: induced merciful oblivion or elimination of abnormal hypermnesia? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471538/ https://www.ncbi.nlm.nih.gov/pubmed/17148840 http://dx.doi.org/10.1155/2006/793256 |
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