UPLC-Tandem Mass Spectrometry Method for Simultaneous Determination of Fluoxetine, Risperidone, and Its Active Metabolite 9-Hydroxyrisperidone in Plasma: Application to Pharmacokinetics Study in Rats

Risperidone (RIS) is used as an antipsychotic drug alone or with other drugs, like fluoxetine (FLX). A simple method was developed and validated for the determination of both RIS and its metabolite 9-hydroxyrisperidone (9-OH-RIS), FLX, and olanzapine (OLA) as an internal standard in rat's plasm...

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Detalles Bibliográficos
Autores principales: Ezzeldin, Essam, Abo-Talib, Nisreen F., Tammam, Marwa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471578/
https://www.ncbi.nlm.nih.gov/pubmed/28656122
http://dx.doi.org/10.1155/2017/5187084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471578/
https://www.ncbi.nlm.nih.gov/pubmed/28656122
http://dx.doi.org/10.1155/2017/5187084

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