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Human IL-6R(hi)TIGIT(−) CD4(+) CD127(low)CD25(+) T cells display potent in vitro suppressive capacity and a distinct Th17 profile

To date many clinical studies aim to increase the number and/or fitness of CD4(+) CD127(low)CD25(+) regulatory T cells (Tregs) in vivo to harness their regulatory potential in the context of treating autoimmune disease. Here, we sought to define the phenotype and function of Tregs expressing the hig...

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Detalles Bibliográficos
Autores principales:	Ferreira, Ricardo C., Rainbow, Daniel B., Rubio García, Arcadio, Pekalski, Marcin L., Porter, Linsey, Oliveira, João J., Waldron-Lynch, Frank, Wicker, Linda S., Todd, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471606/ https://www.ncbi.nlm.nih.gov/pubmed/28284938 http://dx.doi.org/10.1016/j.clim.2017.03.002

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