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An LC-MS Assay with Isocratic Separation and On-line Solid Phase Extraction to Improve the Routine Therapeutic Drug Monitoring of Busulfan in Plasma

BACKGROUND: Busulfan (Bu) requires therapeutic drug monitoring (TDM) in subjects undergoing a conditioning regimen for hematopoietic stem cell transplantation (HSCT). To speed up the procedure and increase reproducibility, we improved our routine LC-MS/MS assay using the on-line solid-phase extracti...

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Detalles Bibliográficos
Autores principales:	Ialongo, Cristiano, Mozzi, Alessia Francesca, Bernardini, Sergio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Medical Biochemists of Serbia 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471643/ https://www.ncbi.nlm.nih.gov/pubmed/28680354 http://dx.doi.org/10.1515/jomb-2016-0031

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