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Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression

BACKGROUND: Oct4, a key stemness transcription factor, is overexpressed in lung cancer. Here, we reveal a novel transcription regulation of long non-coding RNAs (lncRNAs) by Oct4. LncRNAs have emerged as important players in cancer progression. METHODS: Oct4 chromatin-immunoprecipitation (ChIP)-sequ...

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Detalles Bibliográficos
Autores principales:	Jen, Jayu, Tang, Yen-An, Lu, Ying-Hung, Lin, Che-Chung, Lai, Wu-Wei, Wang, Yi-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471675/ https://www.ncbi.nlm.nih.gov/pubmed/28615056 http://dx.doi.org/10.1186/s12943-017-0674-z

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