Cargando…

The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility

BACKGROUND: Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Jégu, Teddy, Veluchamy, Alaguraj, Ramirez-Prado, Juan S., Rizzi-Paillet, Charley, Perez, Magalie, Lhomme, Anaïs, Latrasse, David, Coleno, Emeline, Vicaire, Serge, Legras, Stéphanie, Jost, Bernard, Rougée, Martin, Barneche, Fredy, Bergounioux, Catherine, Crespi, Martin, Mahfouz, Magdy M., Hirt, Heribert, Raynaud, Cécile, Benhamed, Moussa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471679/
https://www.ncbi.nlm.nih.gov/pubmed/28619072
http://dx.doi.org/10.1186/s13059-017-1246-7
_version_ 1783243994021494784
author Jégu, Teddy
Veluchamy, Alaguraj
Ramirez-Prado, Juan S.
Rizzi-Paillet, Charley
Perez, Magalie
Lhomme, Anaïs
Latrasse, David
Coleno, Emeline
Vicaire, Serge
Legras, Stéphanie
Jost, Bernard
Rougée, Martin
Barneche, Fredy
Bergounioux, Catherine
Crespi, Martin
Mahfouz, Magdy M.
Hirt, Heribert
Raynaud, Cécile
Benhamed, Moussa
author_facet Jégu, Teddy
Veluchamy, Alaguraj
Ramirez-Prado, Juan S.
Rizzi-Paillet, Charley
Perez, Magalie
Lhomme, Anaïs
Latrasse, David
Coleno, Emeline
Vicaire, Serge
Legras, Stéphanie
Jost, Bernard
Rougée, Martin
Barneche, Fredy
Bergounioux, Catherine
Crespi, Martin
Mahfouz, Magdy M.
Hirt, Heribert
Raynaud, Cécile
Benhamed, Moussa
author_sort Jégu, Teddy
collection PubMed
description BACKGROUND: Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored. RESULTS: In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms. CONCLUSIONS: These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-017-1246-7) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-5471679
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-54716792017-06-21 The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility Jégu, Teddy Veluchamy, Alaguraj Ramirez-Prado, Juan S. Rizzi-Paillet, Charley Perez, Magalie Lhomme, Anaïs Latrasse, David Coleno, Emeline Vicaire, Serge Legras, Stéphanie Jost, Bernard Rougée, Martin Barneche, Fredy Bergounioux, Catherine Crespi, Martin Mahfouz, Magdy M. Hirt, Heribert Raynaud, Cécile Benhamed, Moussa Genome Biol Research BACKGROUND: Plant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored. RESULTS: In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms. CONCLUSIONS: These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-017-1246-7) contains supplementary material, which is available to authorized users. BioMed Central 2017-06-15 /pmc/articles/PMC5471679/ /pubmed/28619072 http://dx.doi.org/10.1186/s13059-017-1246-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Jégu, Teddy
Veluchamy, Alaguraj
Ramirez-Prado, Juan S.
Rizzi-Paillet, Charley
Perez, Magalie
Lhomme, Anaïs
Latrasse, David
Coleno, Emeline
Vicaire, Serge
Legras, Stéphanie
Jost, Bernard
Rougée, Martin
Barneche, Fredy
Bergounioux, Catherine
Crespi, Martin
Mahfouz, Magdy M.
Hirt, Heribert
Raynaud, Cécile
Benhamed, Moussa
The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
title The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
title_full The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
title_fullStr The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
title_full_unstemmed The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
title_short The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
title_sort arabidopsis swi/snf protein baf60 mediates seedling growth control by modulating dna accessibility
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471679/
https://www.ncbi.nlm.nih.gov/pubmed/28619072
http://dx.doi.org/10.1186/s13059-017-1246-7
work_keys_str_mv AT jeguteddy thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT veluchamyalaguraj thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT ramirezpradojuans thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT rizzipailletcharley thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT perezmagalie thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT lhommeanais thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT latrassedavid thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT colenoemeline thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT vicaireserge thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT legrasstephanie thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT jostbernard thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT rougeemartin thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT barnechefredy thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT bergouniouxcatherine thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT crespimartin thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT mahfouzmagdym thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT hirtheribert thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT raynaudcecile thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT benhamedmoussa thearabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT jeguteddy arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT veluchamyalaguraj arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT ramirezpradojuans arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT rizzipailletcharley arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT perezmagalie arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT lhommeanais arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT latrassedavid arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT colenoemeline arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT vicaireserge arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT legrasstephanie arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT jostbernard arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT rougeemartin arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT barnechefredy arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT bergouniouxcatherine arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT crespimartin arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT mahfouzmagdym arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT hirtheribert arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT raynaudcecile arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility
AT benhamedmoussa arabidopsisswisnfproteinbaf60mediatesseedlinggrowthcontrolbymodulatingdnaaccessibility