Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31

We report the unusual case of a 63-year-old man with spinocerebellar ataxia (SCA) type 31 who developed neuromyelitis optica spectrum disorder (NMOSD) 14 years after the onset of cerebellar symptoms. In addition to cerebellar atrophy, magnetic resonance imaging showed multiple high-intensity areas i...

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Detalles Bibliográficos
Autores principales: Takahashi, Yoshiaki, Manabe, Yasuhiro, Morihara, Ryuta, Narai, Hisashi, Yamashita, Toru, Abe, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471787/
https://www.ncbi.nlm.nih.gov/pubmed/28626410
http://dx.doi.org/10.1159/000475657
Descripción
Sumario:We report the unusual case of a 63-year-old man with spinocerebellar ataxia (SCA) type 31 who developed neuromyelitis optica spectrum disorder (NMOSD) 14 years after the onset of cerebellar symptoms. In addition to cerebellar atrophy, magnetic resonance imaging showed multiple high-intensity areas in the brain and a long thoracic cord lesion from Th1/2 to Th11. The combination of NMOSD and SCA31 is accidental. However, our case suggests that inflammatory processes could be involved in the pathogenesis of NMOSD and SCA31.

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