Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31

We report the unusual case of a 63-year-old man with spinocerebellar ataxia (SCA) type 31 who developed neuromyelitis optica spectrum disorder (NMOSD) 14 years after the onset of cerebellar symptoms. In addition to cerebellar atrophy, magnetic resonance imaging showed multiple high-intensity areas i...

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Autores principales: Takahashi, Yoshiaki, Manabe, Yasuhiro, Morihara, Ryuta, Narai, Hisashi, Yamashita, Toru, Abe, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471787/
https://www.ncbi.nlm.nih.gov/pubmed/28626410
http://dx.doi.org/10.1159/000475657
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author Takahashi, Yoshiaki
Manabe, Yasuhiro
Morihara, Ryuta
Narai, Hisashi
Yamashita, Toru
Abe, Koji
author_facet Takahashi, Yoshiaki
Manabe, Yasuhiro
Morihara, Ryuta
Narai, Hisashi
Yamashita, Toru
Abe, Koji
author_sort Takahashi, Yoshiaki
collection PubMed
description We report the unusual case of a 63-year-old man with spinocerebellar ataxia (SCA) type 31 who developed neuromyelitis optica spectrum disorder (NMOSD) 14 years after the onset of cerebellar symptoms. In addition to cerebellar atrophy, magnetic resonance imaging showed multiple high-intensity areas in the brain and a long thoracic cord lesion from Th1/2 to Th11. The combination of NMOSD and SCA31 is accidental. However, our case suggests that inflammatory processes could be involved in the pathogenesis of NMOSD and SCA31.
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spelling pubmed-54717872017-06-16 Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31 Takahashi, Yoshiaki Manabe, Yasuhiro Morihara, Ryuta Narai, Hisashi Yamashita, Toru Abe, Koji Case Rep Neurol Case Report We report the unusual case of a 63-year-old man with spinocerebellar ataxia (SCA) type 31 who developed neuromyelitis optica spectrum disorder (NMOSD) 14 years after the onset of cerebellar symptoms. In addition to cerebellar atrophy, magnetic resonance imaging showed multiple high-intensity areas in the brain and a long thoracic cord lesion from Th1/2 to Th11. The combination of NMOSD and SCA31 is accidental. However, our case suggests that inflammatory processes could be involved in the pathogenesis of NMOSD and SCA31. S. Karger AG 2017-05-17 /pmc/articles/PMC5471787/ /pubmed/28626410 http://dx.doi.org/10.1159/000475657 Text en Copyright © 2017 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Takahashi, Yoshiaki
Manabe, Yasuhiro
Morihara, Ryuta
Narai, Hisashi
Yamashita, Toru
Abe, Koji
Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31
title Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31
title_full Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31
title_fullStr Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31
title_full_unstemmed Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31
title_short Neuromyelitis Optica Spectrum Disorder Coinciding with Spinocerebellar Ataxia Type 31
title_sort neuromyelitis optica spectrum disorder coinciding with spinocerebellar ataxia type 31
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471787/
https://www.ncbi.nlm.nih.gov/pubmed/28626410
http://dx.doi.org/10.1159/000475657
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