Cargando…

Informed consent for next-generation nucleotide sequencing studies: Aiding communication between participants and investigators

INTRODUCTION: Obtaining informed consent from prospective participants for research studies that include next-generation nucleotide sequencing (NGS) presents significant challenges because of the need to explain all the potential implications of participating, including the possible return of “incid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kost, Rhonda G., Poppel, Stephen M., Coller, Barry S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2017
Materias:	Translational Research, Design and Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471895/ https://www.ncbi.nlm.nih.gov/pubmed/28649453 http://dx.doi.org/10.1017/cts.2016.21

Ejemplares similares

Delivery of the research participant perception survey through the patient portal
por: Kelly-Pumarol, Issis J., et al.
Publicado: (2018)

Rapid clinical diagnostic variant investigation of genomic patient sequencing data with iobio web tools
por: Ward, Alistair, et al.
Publicado: (2018)

The innovation scorecard for continuous improvement applied to translational science
por: Kotarba, Joseph A., et al.
Publicado: (2017)

Effectiveness and cost of recruiting healthy volunteers for clinical research studies using an electronic patient portal: A randomized study
por: Samuels, Mary H., et al.
Publicado: (2018)

Maintenance efficacy designs in psychiatry: Randomized discontinuation trials – enriched but not better
por: Ghaemi, S. N., et al.
Publicado: (2017)

IRB Process Improvements: A Machine Learning Analysis
por: Shoenbill, Kimberly, et al.
Publicado: (2017)

Toward a science of translational science
por: Smith, Caleb, et al.
Publicado: (2017)

Regulatory interfaces surrounding the growing field of additive manufacturing of medical devices and biologic products
por: Adamo, Joan E., et al.
Publicado: (2018)

The integration of emerging omics approaches to advance precision medicine: How can regulatory science help?
por: Adamo, Joan E., et al.
Publicado: (2018)

Opportunities for life course research through the integration of data across Clinical and Translational Research Institutes
por: Hanson, Heidi A., et al.
Publicado: (2018)

Realizing the full potential of precision health: The need to include patient-reported health behavior, mental health, social determinants, and patient preferences data
por: Glasgow, Russell E., et al.
Publicado: (2018)

Uncertainty quantification in breast cancer risk prediction models using self-reported family health history
por: Pflieger, Lance T., et al.
Publicado: (2017)

Patient-Centered Network of Learning Health Systems: Developing a resource for clinical translational research
por: Finney Rutten, L. J., et al.
Publicado: (2017)

Effect of a Clinical and Translational Science Award institute on grant funding in a major research university
por: Kabo, Felichism W., et al.
Publicado: (2017)

Systems approach to assessing and improving local human research Institutional Review Board performance
por: Fontanesi, John, et al.
Publicado: (2018)

Integration of patient and clinician narratives into systematic reviews: An applied proof of concept
por: Christensen, Vivian, et al.
Publicado: (2021)

Rationale, challenges, and participants in a Phase II trial of a botanical product for chronic hepatitis C
por: Reddy, K Rajender, et al.
Publicado: (2012)

Designing a childhood obesity preventive intervention using the multiphase optimization strategy: The Healthy Bodies Project
por: Francis, Lori A, et al.
Publicado: (2023)

Using simulated infectious disease outbreaks to inform site selection and sample size for individually randomized vaccine trials during an ongoing epidemic
por: Madewell, Zachary J, et al.
Publicado: (2021)

Do Bayesian adaptive trials offer advantages for comparative effectiveness research? Protocol for the RE-ADAPT study
por: Connor, Jason T, et al.
Publicado: (2013)

Data based investigation of the energy metering type, billing and usage of sampled residents of Ota Community in Nigeria
por: Adekitan, Aderibigbe Israel, et al.
Publicado: (2018)

Assessment of the understanding of informed consent including participants’ experiences, and generation of a supplemental consent decision aid for Gestational Diabetes Mellitus (GDM) research
por: Atal, Shubham, et al.
Publicado: (2018)

Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population
por: Fry, Anna, et al.
Publicado: (2017)

Redesigning a large school-based clinical trial in response to changes in community practice
por: Gerald, Lynn B, et al.
Publicado: (2011)

Randomized trials of alcohol-use interventions with college students and their parents: lessons from the Transitions Project
por: Fernandez, AC, et al.
Publicado: (2011)

Evaluating the safety of a rotavirus vaccine: the REST of the story
por: Heyse, Joseph F, et al.
Publicado: (2008)

Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer
por: Demark-Wahnefried, Wendy, et al.
Publicado: (2008)

A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen
por: Fiore, Louis D, et al.
Publicado: (2011)

The development and description of the comparison group in the Look AHEAD trial
Publicado: (2011)

Statistical aspects of the TNK-S2B trial of tenecteplase versus alteplase in acute ischemic stroke: an efficient, dose-adaptive, seamless phase II/III design
por: Levin, Bruce, et al.
Publicado: (2011)

Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014–2015 outbreak
por: Edwards, Tansy, et al.
Publicado: (2016)

Design of the HPTN 065 (TLC-Plus) study: A study to evaluate the feasibility of an enhanced test, link-to-care, plus treat approach for HIV prevention in the United States
por: Gamble, Theresa, et al.
Publicado: (2017)

The optimal design of stepped wedge trials with equal allocation to sequences and a comparison to other trial designs
por: Thompson, Jennifer A, et al.
Publicado: (2017)

Data on the Amphidinium carterae Dn241EHU isolation and morphological and molecular characterization
por: Seoane, S., et al.
Publicado: (2018)

Chromatin structure profile data from DNS-seq: Differential nuclease sensitivity mapping of four reference tissues of B73 maize (Zea mays L)
por: Turpin, Zachary M., et al.
Publicado: (2018)

Extensional rheological data from ex-situ measurements for predicting porous media behaviour of the viscoelastic EOR polymers
por: Azad, M.S., et al.
Publicado: (2018)

Technical data of a grid-connected photovoltaic/wind hybrid system with and without storage battery for residential buildings located in a warm area
por: Baglivo, Cristina, et al.
Publicado: (2018)

Dataset for the estimation of costs for direct contact condenser
por: Liu, Dunyu, et al.
Publicado: (2018)

Data on safe hydrogen production from the solar photovoltaic solar panel through alkaline electrolyser under Algerian climate
por: Menad, Chawki Ameur, et al.
Publicado: (2018)

Data on combination of parabolic solar system with CH(4) cycle and power tower solar system with Cu–Cl cycle for hydrogen production in the city of Ghardaia (Algeria)
por: menad, Chawki Ameur, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_uuchl6igoelrifr9m4bihafb8l