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Drug repositioning for enzyme modulator based on human metabolite-likeness

BACKGROUND: Recently, the metabolite-likeness of the drug space has emerged and has opened a new possibility for exploring human metabolite-like candidates in drug discovery. However, the applicability of metabolite-likeness in drug discovery has been largely unexplored. Moreover, there are no repor...

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Detalles Bibliográficos
Autores principales: Lee, Yoon Hyeok, Choi, Hojae, Park, Seongyong, Lee, Boah, Yi, Gwan-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471945/
https://www.ncbi.nlm.nih.gov/pubmed/28617219
http://dx.doi.org/10.1186/s12859-017-1637-5