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Drug repositioning for enzyme modulator based on human metabolite-likeness
BACKGROUND: Recently, the metabolite-likeness of the drug space has emerged and has opened a new possibility for exploring human metabolite-like candidates in drug discovery. However, the applicability of metabolite-likeness in drug discovery has been largely unexplored. Moreover, there are no repor...
Autores principales: | Lee, Yoon Hyeok, Choi, Hojae, Park, Seongyong, Lee, Boah, Yi, Gwan-Su |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471945/ https://www.ncbi.nlm.nih.gov/pubmed/28617219 http://dx.doi.org/10.1186/s12859-017-1637-5 |
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