Integrated pharmacokinetic–Pharmacodynamic (PK/PD) model to evaluate the in vivo antimicrobial activity of Marbofloxacin against Pasteurella multocida in piglets

BACKGROUND: Marbofloxacin is a veterinary fluoroquinolone with high activity against Pasteurella multocida. We evaluated it’s in vivo activity against P. multocida based on in vivo time-kill data in swine using a tissue-cage model. A series of dosages ranging from 0.15 to 2.5 mg/kg were administered...

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Detalles Bibliográficos
Autores principales: Zeng, Qing Lin, Mei, Xian, Su, Jia, Li, Xiao Hong, Xiong, Wen Guang, Lu, Yan, Zeng, Zhen Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471993/
https://www.ncbi.nlm.nih.gov/pubmed/28619095
http://dx.doi.org/10.1186/s12917-017-1099-z

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