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Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field

OBJECTIVE: The behavior of beta particles under the magnetic field was investigated both theoretically and experimentally based on the assumption of reducing the damage to the normal tissues created by using magnetic field in radionuclide therapy. METHODS: A water-filled spherical medium and a beta...

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Autores principales: Çavuşoğlu, Berrin, Sucu, Selda, Durak, Hatice, Akgüngör, Kadir, Epik, Hakan, Ertay, Türkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472087/
https://www.ncbi.nlm.nih.gov/pubmed/28613197
http://dx.doi.org/10.4274/mirt.30932
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author Çavuşoğlu, Berrin
Sucu, Selda
Durak, Hatice
Akgüngör, Kadir
Epik, Hakan
Ertay, Türkan
author_facet Çavuşoğlu, Berrin
Sucu, Selda
Durak, Hatice
Akgüngör, Kadir
Epik, Hakan
Ertay, Türkan
author_sort Çavuşoğlu, Berrin
collection PubMed
description OBJECTIVE: The behavior of beta particles under the magnetic field was investigated both theoretically and experimentally based on the assumption of reducing the damage to the normal tissues created by using magnetic field in radionuclide therapy. METHODS: A water-filled spherical medium and a beta particle source was formed by using Geant4 simulation software for the theoretical study. After applying a homogenous magnetic field, the volume of points at which the particles interact with the medium was calculated by determining particle range. The range of beta particles was examined using yttrium-90 source and Gafchromic films for the experimental study. The setup was kept in normal room conditions and in the magnetic resonance imaging device. Then the irradiated films were analyzed by creating isodose curves. RESULTS: With the increase of the magnetic field, the number of hits at the center was increased, but the number of hits at the outer boundaries decreased inversely proportional to the strength of the magnetic field. The change perpendicular to the magnetic field was greater as compared to the change parallel to the magnetic field. The volume of hits of beta particles got smaller with the increase of the magnetic field. CONCLUSION: When magnetic field is increased, the decrease in the number of interactions at the outer boundaries became more pronounced in the perpendicular direction to the magnetic field. The effect of magnetic field was more apparent for higher energy beta particles than lower energy particles.
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spelling pubmed-54720872017-06-21 Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field Çavuşoğlu, Berrin Sucu, Selda Durak, Hatice Akgüngör, Kadir Epik, Hakan Ertay, Türkan Mol Imaging Radionucl Ther Original Article OBJECTIVE: The behavior of beta particles under the magnetic field was investigated both theoretically and experimentally based on the assumption of reducing the damage to the normal tissues created by using magnetic field in radionuclide therapy. METHODS: A water-filled spherical medium and a beta particle source was formed by using Geant4 simulation software for the theoretical study. After applying a homogenous magnetic field, the volume of points at which the particles interact with the medium was calculated by determining particle range. The range of beta particles was examined using yttrium-90 source and Gafchromic films for the experimental study. The setup was kept in normal room conditions and in the magnetic resonance imaging device. Then the irradiated films were analyzed by creating isodose curves. RESULTS: With the increase of the magnetic field, the number of hits at the center was increased, but the number of hits at the outer boundaries decreased inversely proportional to the strength of the magnetic field. The change perpendicular to the magnetic field was greater as compared to the change parallel to the magnetic field. The volume of hits of beta particles got smaller with the increase of the magnetic field. CONCLUSION: When magnetic field is increased, the decrease in the number of interactions at the outer boundaries became more pronounced in the perpendicular direction to the magnetic field. The effect of magnetic field was more apparent for higher energy beta particles than lower energy particles. Galenos Publishing 2017-06 2017-06-01 /pmc/articles/PMC5472087/ /pubmed/28613197 http://dx.doi.org/10.4274/mirt.30932 Text en ©Copyright 2017 by Turkish Society of Nuclear Medicine / Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Çavuşoğlu, Berrin
Sucu, Selda
Durak, Hatice
Akgüngör, Kadir
Epik, Hakan
Ertay, Türkan
Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field
title Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field
title_full Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field
title_fullStr Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field
title_full_unstemmed Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field
title_short Experimental and Simulation Analysis of Radiation of the Beta Emitting Sources in a Magnetic Field
title_sort experimental and simulation analysis of radiation of the beta emitting sources in a magnetic field
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472087/
https://www.ncbi.nlm.nih.gov/pubmed/28613197
http://dx.doi.org/10.4274/mirt.30932
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