Cargando…

Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis

Ebola virus (EBOV) is an enveloped negative-sense RNA virus that causes sporadic outbreaks with high case fatality rates. Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with additional roles in the replication cycle such as vira...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Wei, Luthra, Priya, Wu, Chao, Batra, Jyoti, Leung, Daisy W., Basler, Christopher F., Amarasinghe, Gaya K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472179/ https://www.ncbi.nlm.nih.gov/pubmed/28593988 http://dx.doi.org/10.1038/ncomms15576

Ejemplares similares

Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules
por: Ma, Yan-hong, et al.
Publicado: (2023)

The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis
por: Kirchdoerfer, Robert N., et al.
Publicado: (2016)

The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing
por: Dilley, Kari A., et al.
Publicado: (2017)

The two-stage interaction of Ebola virus VP40 with nucleoprotein results in a switch from viral RNA synthesis to virion assembly/budding
por: Wu, Linjuan, et al.
Publicado: (2020)

Identification of Continuous Human B-Cell Epitopes in the VP35, VP40, Nucleoprotein and Glycoprotein of Ebola Virus
por: Becquart, Pierre, et al.
Publicado: (2014)

A cryptic pocket in Ebola VP35 allosterically controls RNA binding
por: Cruz, Matthew A., et al.
Publicado: (2022)

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication
por: Shabman, Reed S., et al.
Publicado: (2013)

Cryo-EM analysis of Ebola virus nucleocapsid-like assembly
por: Wang, Yan, et al.
Publicado: (2021)

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24
por: Ramanathan, Palaniappan, et al.
Publicado: (2023)

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies
por: Boggs, Kerri Beth, et al.
Publicado: (2022)

Characterization of the Ebola virus nucleoprotein–RNA complex
por: Noda, Takeshi, et al.
Publicado: (2010)

Integrated Computational Approach for Virtual Hit Identification against Ebola Viral Proteins VP35 and VP40
por: Mirza, Muhammad Usman, et al.
Publicado: (2016)

Filoviral Immune Evasion Mechanisms
por: Ramanan, Parameshwaran, et al.
Publicado: (2011)

Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene
por: Edwards, Megan R., et al.
Publicado: (2022)

Host factor SMYD3 is recruited by Ebola virus nucleoprotein to facilitate viral mRNA transcription
por: Chen, Jingliang, et al.
Publicado: (2019)

Structural insights into RNA recognition and activation of RIG-I-like receptors
por: Leung, Daisy W, et al.
Publicado: (2012)

When your cap matters: structural insights into self vs non-self recognition of 5′ RNA by immunomodulatory host proteins
por: Leung, Daisy W, et al.
Publicado: (2016)

Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly
por: van Tol, Sarah, et al.
Publicado: (2022)

Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles
por: Pleet, Michelle L, et al.
Publicado: (2018)

Nucleotide resolution mapping of influenza A virus nucleoprotein-RNA interactions reveals RNA features required for replication
por: Williams, Graham D., et al.
Publicado: (2018)

Rapid detection of an Ebola biomarker with optical microring resonators
por: Qavi, Abraham J., et al.
Publicado: (2022)

Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology
por: Johnson, Reed F, et al.
Publicado: (2006)

Disorder–Order Transitions in Conformational Selection of a Peptide by Ebola Virus Nucleoprotein
por: Olson, Mark A.
Publicado: (2020)

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion
por: Luthra, Priya, et al.
Publicado: (2017)

Aptamers in Virology: Recent Advances and Challenges
por: Binning, Jennifer M., et al.
Publicado: (2012)

The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression
por: Wendt, Lisa, et al.
Publicado: (2020)

Influenza A Virus Nucleoprotein Activates the JNK Stress-Signaling Pathway for Viral Replication by Sequestering Host Filamin A Protein
por: Sharma, Anshika, et al.
Publicado: (2020)

Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities
por: Rodríguez-Salazar, Carlos A., et al.
Publicado: (2023)

Interaction of Influenza A Nucleoprotein with Host hnRNP-C Is Implicated in Viral Replication
por: Tang, Yun-Sang, et al.
Publicado: (2022)

Membrane binding and bending in Ebola VP40 assembly and egress
por: Stahelin, Robert V.
Publicado: (2014)

Regulation of Ebola virus VP40 matrix protein by SUMO
por: Baz-Martínez, Maite, et al.
Publicado: (2016)

The quest for effective Ebola treatment: Ebola VP35 is an evidence-based target for dsRNA drugs
por: Mitchell, William M, et al.
Publicado: (2014)

Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein
por: Morwitzer, M. Jane, et al.
Publicado: (2019)

Ebola virus inclusion bodies are liquid organelles whose formation is facilitated by nucleoprotein oligomerization
por: Bodmer, Bianca S., et al.
Publicado: (2023)

Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging
por: Banadyga, Logan, et al.
Publicado: (2017)

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111
por: Lin, Aaron E., et al.
Publicado: (2020)

A Loop Region in the N-Terminal Domain of Ebola Virus VP40 Is Important in Viral Assembly, Budding, and Egress
por: Adu-Gyamfi, Emmanuel, et al.
Publicado: (2014)

The Ebola Virus VP35 Protein Is a Suppressor of RNA Silencing
por: Haasnoot, Joost, et al.
Publicado: (2007)

Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction
por: Pleet, Michelle L., et al.
Publicado: (2016)

Cheminformatics-Based Study Identifies Potential Ebola VP40 Inhibitors
por: Broni, Emmanuel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dgvqr2qr57i89eqks88ape5mrl