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Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells
BACKGROUND: Oxidative stress is thought to be a key player in the pathogenesis of neurodegenerative dementia, including Alzheimer’s disease (AD). It has been assumed that oxidative stress contributes to the ß-amyloid deposition in cerebral blood vessels. METHODS: In order to prove this hypothesis, w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472258/ https://www.ncbi.nlm.nih.gov/pubmed/28617802 http://dx.doi.org/10.1371/journal.pone.0178127 |