Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

PURPOSE: Despite multimodal therapy, prognosis of pediatric intracranial ependymomas remains poor with a 5-year survival rate below 70% and frequent late deaths. EXPERIMENTAL DESIGN: This multicentric European study evaluated putative prognostic biomarkers. Tenascin-C (TNC) immunohistochemical expre...

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Detalles Bibliográficos
Autores principales: Andreiuolo, Felipe, Le Teuff, Gwénaël, Bayar, Mohamed Amine, Kilday, John-Paul, Pietsch, Torsten, von Bueren, André O., Witt, Hendrik, Korshunov, Andrey, Modena, Piergiorgio, Pfister, Stefan M., Pagès, Mélanie, Castel, David, Giangaspero, Felice, Chimelli, Leila, Varlet, Pascale, Rutkowski, Stefan, Frappaz, Didier, Massimino, Maura, Grundy, Richard, Grill, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472261/
https://www.ncbi.nlm.nih.gov/pubmed/28617804
http://dx.doi.org/10.1371/journal.pone.0178351

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