NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination

Immunodeficient mice transplanted with human peripheral blood mononuclear cells (PBMCs) are promising tools to evaluate human immune responses to vaccines. However, these mice usually develop severe graft-versus-host disease (GVHD), which makes estimation of antigen-specific IgG production after ant...

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Detalles Bibliográficos
Autores principales: Kametani, Yoshie, Katano, Ikumi, Miyamoto, Asuka, Kikuchi, Yusuke, Ito, Ryoji, Muguruma, Yukari, Tsuda, Banri, Habu, Sonoko, Tokuda, Yutaka, Ando, Kiyoshi, Ito, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472286/
https://www.ncbi.nlm.nih.gov/pubmed/28617827
http://dx.doi.org/10.1371/journal.pone.0179239

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