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Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields

Somatosensory evoked fields (SEFs) to electrical stimulation on the right and left sides of the lower lip were measured using magnetoencephalography and compared in the bilateral hemispheres of 31 healthy normal young and 29 healthy normal elderly subjects to evaluate age-related change in lip somat...

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Autores principales: Hihara, Hiroki, Kanetaka, Hiroyasu, Kanno, Akitake, Koeda, Satoko, Nakasato, Nobukazu, Kawashima, Ryuta, Sasaki, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472294/
https://www.ncbi.nlm.nih.gov/pubmed/28617862
http://dx.doi.org/10.1371/journal.pone.0179323
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author Hihara, Hiroki
Kanetaka, Hiroyasu
Kanno, Akitake
Koeda, Satoko
Nakasato, Nobukazu
Kawashima, Ryuta
Sasaki, Keiichi
author_facet Hihara, Hiroki
Kanetaka, Hiroyasu
Kanno, Akitake
Koeda, Satoko
Nakasato, Nobukazu
Kawashima, Ryuta
Sasaki, Keiichi
author_sort Hihara, Hiroki
collection PubMed
description Somatosensory evoked fields (SEFs) to electrical stimulation on the right and left sides of the lower lip were measured using magnetoencephalography and compared in the bilateral hemispheres of 31 healthy normal young and 29 healthy normal elderly subjects to evaluate age-related change in lip somatosensation. The initial peak of the response around 13 ms, designated as N13m, and the second peak of the response, designated as P21m, were investigated. The N13m response, which was detected in 22 of 62 hemispheres in young adults and 37 of 58 hemispheres in elderly adults, showed significantly prolonged latency and increased equivalent current dipole (ECD) moment in the elderly adults. The P21m response, which was detected in 56 of 62 hemispheres in young adults and in 52 of 58 hemispheres in elderly adults, showed longer peak latency in the elderly adults. No significant difference was found in the ECD moment for P21m, which suggests that aging affected the SEFs of the lip somatosensation, but the effects of aging on N13m and P21m differed. Prolonged latency and increased ECD moment of N13m might result from decreased peripheral conduction and increased cortical excitation system associated with aging. Therefore, the initial response component might be an objective parameter for investigating change in lip function with age.
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spelling pubmed-54722942017-07-03 Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields Hihara, Hiroki Kanetaka, Hiroyasu Kanno, Akitake Koeda, Satoko Nakasato, Nobukazu Kawashima, Ryuta Sasaki, Keiichi PLoS One Research Article Somatosensory evoked fields (SEFs) to electrical stimulation on the right and left sides of the lower lip were measured using magnetoencephalography and compared in the bilateral hemispheres of 31 healthy normal young and 29 healthy normal elderly subjects to evaluate age-related change in lip somatosensation. The initial peak of the response around 13 ms, designated as N13m, and the second peak of the response, designated as P21m, were investigated. The N13m response, which was detected in 22 of 62 hemispheres in young adults and 37 of 58 hemispheres in elderly adults, showed significantly prolonged latency and increased equivalent current dipole (ECD) moment in the elderly adults. The P21m response, which was detected in 56 of 62 hemispheres in young adults and in 52 of 58 hemispheres in elderly adults, showed longer peak latency in the elderly adults. No significant difference was found in the ECD moment for P21m, which suggests that aging affected the SEFs of the lip somatosensation, but the effects of aging on N13m and P21m differed. Prolonged latency and increased ECD moment of N13m might result from decreased peripheral conduction and increased cortical excitation system associated with aging. Therefore, the initial response component might be an objective parameter for investigating change in lip function with age. Public Library of Science 2017-06-15 /pmc/articles/PMC5472294/ /pubmed/28617862 http://dx.doi.org/10.1371/journal.pone.0179323 Text en © 2017 Hihara et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Hihara, Hiroki
Kanetaka, Hiroyasu
Kanno, Akitake
Koeda, Satoko
Nakasato, Nobukazu
Kawashima, Ryuta
Sasaki, Keiichi
Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
title Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
title_full Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
title_fullStr Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
title_full_unstemmed Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
title_short Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
title_sort evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472294/
https://www.ncbi.nlm.nih.gov/pubmed/28617862
http://dx.doi.org/10.1371/journal.pone.0179323
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