Three mutations switch H7N9 influenza to human-type receptor specificity

The avian H7N9 influenza outbreak in 2013 resulted from an unprecedented incidence of influenza transmission to humans from infected poultry. The majority of human H7N9 isolates contained a hemagglutinin (HA) mutation (Q226L) that has previously been associated with a switch in receptor specificity...

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Detalles Bibliográficos
Autores principales: de Vries, Robert P., Peng, Wenjie, Grant, Oliver C., Thompson, Andrew J., Zhu, Xueyong, Bouwman, Kim M., de la Pena, Alba T. Torrents, van Breemen, Marielle J., Ambepitiya Wickramasinghe, Iresha N., de Haan, Cornelis A. M., Yu, Wenli, McBride, Ryan, Sanders, Rogier W., Woods, Robert J., Verheije, Monique H., Wilson, Ian A., Paulson, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472306/
https://www.ncbi.nlm.nih.gov/pubmed/28617868
http://dx.doi.org/10.1371/journal.ppat.1006390

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