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Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis

T-cell proliferation and generation of protective memory during chronic infections depend on Interleukin-7 (IL-7) availability and receptivity. Regulation of IL-7 receptor (IL-7R) expression and signalling are key for IL-7-modulated T-cell functions. Aberrant expression of soluble (s) and membrane-a...

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Detalles Bibliográficos
Autores principales:	Lundtoft, Christian, Afum-Adjei Awuah, Anthony, Rimpler, Jens, Harling, Kirstin, Nausch, Norman, Kohns, Malte, Adankwah, Ernest, Lang, Franziska, Olbrich, Laura, Mayatepek, Ertan, Owusu-Dabo, Ellis, Jacobsen, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472333/ https://www.ncbi.nlm.nih.gov/pubmed/28582466 http://dx.doi.org/10.1371/journal.ppat.1006425

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