The miR-487b-3p/GRM3/TGFβ signaling axis is an important regulator of colon cancer tumorigenesis

Molecular targeting is an import strategy to treat advanced colon cancer. The current study demonstrates that expression of GRM3, a metabotropic glutamate receptor mainly expressed in mammalian central nervous system, is significantly upregulated in majority of human colonic adenocarcinomas tested a...

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Detalles Bibliográficos
Autores principales: Yi, Haowei, Geng, Liying, Black, Adrian, Talmon, Geoff, Berim, Lyudmyla, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472494/
https://www.ncbi.nlm.nih.gov/pubmed/28114282
http://dx.doi.org/10.1038/onc.2016.499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472494/
https://www.ncbi.nlm.nih.gov/pubmed/28114282
http://dx.doi.org/10.1038/onc.2016.499

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