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The miR-487b-3p/GRM3/TGFβ signaling axis is an important regulator of colon cancer tumorigenesis
Molecular targeting is an import strategy to treat advanced colon cancer. The current study demonstrates that expression of GRM3, a metabotropic glutamate receptor mainly expressed in mammalian central nervous system, is significantly upregulated in majority of human colonic adenocarcinomas tested a...
Autores principales: | Yi, Haowei, Geng, Liying, Black, Adrian, Talmon, Geoff, Berim, Lyudmyla, Wang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472494/ https://www.ncbi.nlm.nih.gov/pubmed/28114282 http://dx.doi.org/10.1038/onc.2016.499 |
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