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Mechanical stability of talin rod controls cell migration and substrate sensing
Cells adhere to the surrounding tissue and probe its mechanical properties by forming cell-matrix adhesions. Talin is a critical adhesion protein and participates in the transmission of mechanical signals between extracellular matrix and cell cytoskeleton. Force induced unfolding of talin rod subdom...
Autores principales: | Rahikainen, Rolle, von Essen, Magdaléna, Schaefer, Markus, Qi, Lei, Azizi, Latifeh, Kelly, Conor, Ihalainen, Teemu O., Wehrle-Haller, Bernhard, Bastmeyer, Martin, Huang, Cai, Hytönen, Vesa P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472591/ https://www.ncbi.nlm.nih.gov/pubmed/28620171 http://dx.doi.org/10.1038/s41598-017-03335-2 |
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