A non-ionotropic activity of NMDA receptors contributes to glycine-induced neuroprotection in cerebral ischemia-reperfusion injury

NMDA receptor (NMDAR) is known for its ionotropic function. But recent evidence suggests that NMDAR also has a non-ionotropic property. To determine the role of non-ionotropic activity of NMDARs in clinical relevant conditions, we tested the effect of glycine, a co-agonist of NMDARs, in rat middle c...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Juan, Hu, Rong, Liao, Huabao, Zhang, Ya, Lei, Ruixue, Zhang, Zhifeng, Zhuang, Yang, Wan, Yu, Jin, Ping, Feng, Hua, Wan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472592/
https://www.ncbi.nlm.nih.gov/pubmed/28620235
http://dx.doi.org/10.1038/s41598-017-03909-0

Ejemplares similares

Ejemplares similares