Specific ablation of mouse Fam20C in cells expressing type I collagen leads to skeletal defects and hypophosphatemia

FAM20C mutations in humans cause Raine syndrome and our previous studies showed that global inactivation of mouse Fam20C led to bone and dental defects. By crossbreeding 2.3  kb Col 1a1-Cre mice with Fam20C (flox/flox) mice, we created 2.3  kb Col 1a1-Cre;Fam20C (foxl/flox) (cKO) mice, in which Fam2...

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Detalles Bibliográficos
Autores principales: Liu, Peihong, Ma, Su, Zhang, Hua, Liu, Chao, Lu, Yongbo, Chen, Li, Qin, Chunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472603/
https://www.ncbi.nlm.nih.gov/pubmed/28620244
http://dx.doi.org/10.1038/s41598-017-03960-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472603/
https://www.ncbi.nlm.nih.gov/pubmed/28620244
http://dx.doi.org/10.1038/s41598-017-03960-x

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