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Molecular dynamics exploration of poration and leaking caused by Kalata B1 in HIV-infected cell membrane compared to host and HIV membranes

The membrane disruption activities of kalata B1 (kB1) were investigated using molecular dynamics simulations with membrane models. The models were constructed to mimic the lipid microdomain formation in membranes of HIV particle, HIV-infected cell, and host cell. The differences in the lipid ratios...

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Detalles Bibliográficos
Autores principales: Nawae, Wanapinun, Hannongbua, Supa, Ruengjitchatchawalya, Marasri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472625/
https://www.ncbi.nlm.nih.gov/pubmed/28620219
http://dx.doi.org/10.1038/s41598-017-03745-2