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Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin
Small molecule ligands that could stabilize G-quadruplex structure formed at the promoter region of human c-myc oncogene will regulate its expression in cancer cells. Flavonoids, a group of naturally available small molecule, have been known for their various promising effects on human health. In pr...
Autores principales: | Tawani, Arpita, Mishra, Subodh Kumar, Kumar, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472631/ https://www.ncbi.nlm.nih.gov/pubmed/28620169 http://dx.doi.org/10.1038/s41598-017-03906-3 |
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