Differentially Severe Cognitive Effects of Compromised Cerebral Blood Flow in Aged Mice: Association with Myelin Degradation and Microglia Activation

Bilateral common carotid artery stenosis (BCAS) models the effects of compromised cerebral blood flow on brain structure and function in mice. We compared the effects of BCAS in aged (21 month) and young adult (3 month) female mice, anticipating a differentially more severe effect in the older mice....

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Detalles Bibliográficos
Autores principales: Wolf, Gilly, Lotan, Amit, Lifschytz, Tzuri, Ben-Ari, Hagar, Kreisel Merzel, Tirzah, Tatarskyy, Pavel, Valitzky, Michael, Mernick, Ben, Avidan, Elad, Koroukhov, Nickolay, Lerer, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472721/
https://www.ncbi.nlm.nih.gov/pubmed/28670274
http://dx.doi.org/10.3389/fnagi.2017.00191

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