Aged induced pluripotent stem cell (iPSCs) as a new cellular model for studying premature aging

Nuclear integrity and mechanical stability of the nuclear envelope (NE) are conferred by the nuclear lamina, a meshwork of intermediate filaments composed of A- and B-type lamins, supporting the inner nuclear membrane and playing a pivotal role in chromatin organization and epigenetic regulation. Du...

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Detalles Bibliográficos
Autores principales: Petrini, Stefania, Borghi, Rossella, D'Oria, Valentina, Restaldi, Fabrizia, Moreno, Sandra, Novelli, Antonio, Bertini, Enrico, Compagnucci, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472744/
https://www.ncbi.nlm.nih.gov/pubmed/28562315
http://dx.doi.org/10.18632/aging.101248

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