Raptor regulates functional maturation of murine beta cells

Diabetes is associated with beta cell mass loss and islet dysfunctions. mTORC1 regulates beta cell survival, proliferation and function in physiological and pathological conditions, such as pregnancy and pancreatectomy. Here we show that deletion of Raptor, which is an essential component of mTORC1,...

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Detalles Bibliográficos
Autores principales: Ni, Qicheng, Gu, Yanyun, Xie, Yun, Yin, Qinglei, Zhang, Hongli, Nie, Aifang, Li, Wenyi, Wang, Yanqiu, Ning, Guang, Wang, Weiqing, Wang, Qidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472774/
https://www.ncbi.nlm.nih.gov/pubmed/28598424
http://dx.doi.org/10.1038/ncomms15755

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