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Heterologous expression of an α-amylase inhibitor from common bean (Phaseolus vulgaris) in Kluyveromyces lactis and Saccharomyces cerevisiae

BACKGROUND: Phaseolamin or α-amylase inhibitor 1 (αAI) is a glycoprotein from common beans (Phaseolus vulgaris L.) that inhibits some insect and mammalian α-amylases. Several clinical studies support the beneficial use of bean αAI for control of diabetes and obesity. Commercial extracts of P. vulgar...

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Detalles Bibliográficos
Autores principales: Brain-Isasi, Stephanie, Álvarez-Lueje, Alejandro, Higgins, Thomas Joseph V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472880/
https://www.ncbi.nlm.nih.gov/pubmed/28619052
http://dx.doi.org/10.1186/s12934-017-0719-4