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Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases
BACKGROUND: Conjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial. CASE PRESENTATION: We present two cases of Mooren’s ulcer that were treated u...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472947/ https://www.ncbi.nlm.nih.gov/pubmed/28619029 http://dx.doi.org/10.1186/s12886-017-0488-1 |
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author | Li, Saiqun Deng, Yuqing Du, Caiyuan Huang, Haixiang Zhong, Jing Chen, Ling Wang, Bowen Yuan, Jin |
author_facet | Li, Saiqun Deng, Yuqing Du, Caiyuan Huang, Haixiang Zhong, Jing Chen, Ling Wang, Bowen Yuan, Jin |
author_sort | Li, Saiqun |
collection | PubMed |
description | BACKGROUND: Conjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial. CASE PRESENTATION: We present two cases of Mooren’s ulcer that were treated using conjunctival flap in an attempt to prevent further corneal perforation at their local hospital. A rapid acceleration in ulcer progression was observed after a conjunctival flap was applied. Ultimately, the two patients underwent corneal transplantation, which required the postoperative use of topical immunosuppressants and resulted in a final cure. In the current report, we also discussed this incorrect surgical choice via a review of conventional interventions that are used to treat Mooren’s ulcer. CONCLUSIONS: These two cases demonstrate that keratoplasty combined with topical immunosuppressants is effective in treating Mooren’s ulcer. Application of conjunctival flaps or autografting could promote progression of ulceration in Mooren’s ulcers. |
format | Online Article Text |
id | pubmed-5472947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-54729472017-06-21 Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases Li, Saiqun Deng, Yuqing Du, Caiyuan Huang, Haixiang Zhong, Jing Chen, Ling Wang, Bowen Yuan, Jin BMC Ophthalmol Case Report BACKGROUND: Conjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial. CASE PRESENTATION: We present two cases of Mooren’s ulcer that were treated using conjunctival flap in an attempt to prevent further corneal perforation at their local hospital. A rapid acceleration in ulcer progression was observed after a conjunctival flap was applied. Ultimately, the two patients underwent corneal transplantation, which required the postoperative use of topical immunosuppressants and resulted in a final cure. In the current report, we also discussed this incorrect surgical choice via a review of conventional interventions that are used to treat Mooren’s ulcer. CONCLUSIONS: These two cases demonstrate that keratoplasty combined with topical immunosuppressants is effective in treating Mooren’s ulcer. Application of conjunctival flaps or autografting could promote progression of ulceration in Mooren’s ulcers. BioMed Central 2017-06-15 /pmc/articles/PMC5472947/ /pubmed/28619029 http://dx.doi.org/10.1186/s12886-017-0488-1 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Li, Saiqun Deng, Yuqing Du, Caiyuan Huang, Haixiang Zhong, Jing Chen, Ling Wang, Bowen Yuan, Jin Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases |
title | Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases |
title_full | Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases |
title_fullStr | Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases |
title_full_unstemmed | Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases |
title_short | Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases |
title_sort | rapid deterioration of mooren’s ulcers after conjunctival flap: a review of 2 cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472947/ https://www.ncbi.nlm.nih.gov/pubmed/28619029 http://dx.doi.org/10.1186/s12886-017-0488-1 |
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