Cargando…
Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism
BACKGROUND: Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagnostic symptoms of ASD. To enable the earliest stages of therapeutic discovery an...
Autores principales: | Dhamne, Sameer C., Silverman, Jill L., Super, Chloe E., Lammers, Stephen H. T., Hameed, Mustafa Q., Modi, Meera E., Copping, Nycole A., Pride, Michael C., Smith, Daniel G., Rotenberg, Alexander, Crawley, Jacqueline N., Sahin, Mustafa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472997/ https://www.ncbi.nlm.nih.gov/pubmed/28638591 http://dx.doi.org/10.1186/s13229-017-0142-z |
Ejemplares similares
-
Seizure reduction in TSC2‐mutant mouse model by an mTOR catalytic inhibitor
por: Dhamne, Sameer C., et al.
Publicado: (2023) -
Transcranial magnetic stimulation tracks subminute changes in cortical excitability during propofol anesthesia
por: Gersner, Roman, et al.
Publicado: (2020) -
Emerging Gene and Small Molecule Therapies for the Neurodevelopmental Disorder Angelman Syndrome
por: Copping, Nycole A., et al.
Publicado: (2021) -
Intestinal dysmotility in a zebrafish (Danio rerio) shank3a;shank3b mutant model of autism
por: James, David M., et al.
Publicado: (2019) -
A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder
por: Loureiro, Livia O., et al.
Publicado: (2021)